Ascomycin is a 23-membered macrolide lactone that is produced by the fermentation of Streptomyces hygroscopicus and shows strong immunosuppressant properties. It is an ethyl analog of FK506 and blocks the peptidyl-prolyl cis-trans isomerase activity of the protein via binding to FK-506-binding protein (FKBP12). It has a role as an immunosuppressive agent and reduces the production of IL-2, IL-4 and IL-10, and also blocking the mast cell allergic response. It also plays a role as an antifungal agent and a bacterial metabolite.
Product Specifications:
Catalog Number: ZXB-08-138
CAS Number: 104987-12-4/11011-38-4
Formula: C43H69NO12
Molecular Weight: 792.0
Concentration: >98%
Storage: -20°C
PubChem Chemical ID: 5282071
192,00 €
Final price excl. shipping costs2
Free shipping to the following countries: Show more Show less
Ordering: You can also order using info[at]zellx.de or FAX at +49(0)731 55211719
Technical Support: Customer satisfaction is very important to us. Please call us at +49(0)731 55211521 or send an email to technical[at]zellx.de with your technical questions. A member of our scientific staff will be glad to assist you.