Tris base


Tris base, also known as Tris(hydroxymethyl)aminomethane or tris(hydroxymethyl)aminoethane, is a commonly used chemical compound in biological and biochemical research. It is a white crystalline powder with the chemical formula C4H11NO3 and a molecular weight of approximately 121.14 g/mol. Tris base is an effective buffering agent and is often used to prepare buffer solutions with a specific pH value. It can act as both a weak acid and a weak base, making it an ideal choice for maintaining a stable pH in a variety of experimental procedures.


The pKa (acid dissociation constant) of tris base is around 8.1 at 25°C. It is often used to prepare Tris buffer, which is a widely used buffer solution in biological and biochemical studies. Tris buffer is effective in maintaining a stable pH in the range of 7.0 to 9.0, which is useful for many laboratory techniques and experiments involving enzymes, proteins, and nucleic acids. Tris base is also used in various applications, including electrophoresis, DNA and RNA isolation, and enzyme assays. It is an essential and versatile reagent in the laboratory due to its buffering properties and biocompatibility with biological systems.


Product Specifications:

Catalog Number: ZXB-06-194

CAS Number: 77-86-1

Synonyms: 2-Amino-2-(hydroxymethyl)-1,3-propanediol; THAM; Trometamol;  Tris(hydroxymethyl)aminomethane


Formula: C4H11NO3

Molecular Weight: 121.14 g/mol

Storage: RT

PubChem Chemical ID: 6503



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